产品货号:
Z16535
中文名称:
EXOSC2抗体
英文名称:
Anti-EXOSC2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-EXOSC2 Antibody |
指标别名 | EXOSC2;exosome component 2;hRrp4p;p7;RRP4;Rrp4p |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,IHC,FCM,ELISA |
基因名称 | EXOSC2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human RRP4/EXOSC2 recombinant protein (Position:R62-G293). |
实际分子量 | 33KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Exosome component 2,also known as EXOSC2,is a protein which in humans is encoded by the EXOSC2 gene.In the nucleus,the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA,snoRNA and snRNA,in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts,such as antisense RNA species and promoter-upstream transcripts (PROMPTs),and of mRNAs with processing defects,thereby limiting or excluding their export to the cytoplasm.In the cytoplasm,the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions,and in RNA surveillance pathways,preventing translation of aberrant mRNAs.EXOSC2 is a non-catalytic component of the RNA exosome complex that has 3'->5' exoribonuclease activity and involves in a multitude of cellular RNA processing and degradation events. |
Uniprot ID | Q13868 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | exosome component 2 |
蛋白名全称 | Exosome complex component RRP4 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells ELISA 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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